SOD activity, NOx, SH level in wobbler mice
نویسندگان
چکیده
منابع مشابه
SOD3 and eNOS genotypes are associated with SOD activity and NOx
Oxidative stress, characterized by increased reactive oxygen species production and/or decreased antioxidant enzyme activity, plays an important role in the pathogenesis of hypertension. The identification of molecular markers corresponding to the oxidative stress status of hypertension may assist in the antioxidant therapy of hypertension. In the present study, superoxide dismutase (SOD) and e...
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What is Wobbler Syndrome? Wobbler Syndrome is a neurologic disease of dogs that a!ects their spines in the neck region. It is a very important and common cause of neurologic disability in large-breed dogs. Are there other names for Wobbler Syndrome? Wobbler Syndrome or Wobblers is the most common name used, but the veterinary literature has used 14 di!erent names to describe this condition. "is...
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Angiotensin II (Ang II) levels are increased in patients with diabetes, but mechanisms underlying its contribution to diabetic vascular diseases are incompletely understood. We recently reported that in aortic endothelial cells, Ang II induces endothelial nitric oxide synthase (eNOS) uncoupling to produce superoxide (O(2)*(-)) rather than nitric oxide (NO*), upon loss of the tetrahydrobiopterin...
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BACKGROUND Dysfunctionally uncoupled endothelial nitric oxide synthase (eNOS) is involved in producing reactive oxygen species (ROS) in the diabetic endothelium. The present study investigated whether anti-diabetes drug Aminoguanidine (AG) has any effect on eNOS function and vascular oxidant stress. METHODS AND RESULTS Blood glucose levels were increased to 452.0 +/- 15.1 mg/dl in STZ-treated...
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A convincing body of cell culture, animal, and epidemiological studies have provided support and plausible biological mechanisms of a role for lipid oxidation in atherogenesis.1,2 Oxidized structures associated with lipoproteins, primarily LDL, have been shown to be abundant in atherosclerotic plaques.3 The observation that cultured macrophages take up oxidized LDL through a family of scavenger...
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ژورنال
عنوان ژورنال: Ensho
سال: 1999
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.20.57